The best solution is diet and exercise like everyone says, there really is no replacement for them.
Since you asked specifically about medicines then there are three routes.
a). The first one is fat burning pills which in my opinion are a health hazard, what they do is speed up your metabolism so you burn calories faster. There are however long term negative side effects including onset of early diabetes.
. Homeopathic doctors also have fast weight loss medicines with lesser side effects.
c). I also once used this herbal water thing by health and herbs to cut down on some fat deposits that just wouldn't go away with exercise. It's very costly, about 1,200 per day but you loose one pound per day easy with that. The other positive thing about it that I noticed was I was expecting to gain back that weight really fast but it stayed off. Give them a try if you want, although perhaps it's a desi form of increasing your metabolism.
Either way, I would not recommend anything that unnaturally decreases your body weight, you gained it naturally and the healthy way is to lose it naturally via a daily walk of about 5 km's everyday and total boycott of sugars. 10 kg's can be naturally lost in about 3 months easy.