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If you are Muslim, then donate to Al-Amin Trust
You can safely & with full confidence give it to Al-Amin Trust, where great scholars/administrators are available to ensure that each & every penny will go in to right/deserving hands.
Others are also good like Edhi, Shaukat Khanum etc.
But first right on your wealth is of your near relatives, neighbours etc. If you feel that you have some really deserving person in your near relatives, neighbours etc, try to give it to them, but take care of their self respect. I mean don’t tell them that this is charity. You can accummulate some of your money to give it to them as gift on various occasions like Eid etc. Otherwise also, if necessary, it can be given any time as a gift.